Journal of Allergy & Therapy

Johanna Wickemeyer

Publications

• Research Article
  An Alternative Aspirin Desensitization Protocol for Patients with Aspirin- Exacerbated Respiratory Disease
  Author(s): Darshan Patel, Johanna Wickemeyer and Sudhir Sekhsariav Darshan Patel, Johanna Wickemeyer and Sudhir Sekhsariav
  
  Background:Aspirin exacerbated respiratory disease (AERD) affects up to 5% to 15% of asthmatics. While aspirin desensitization is a safe treatment option and allows for aspirin to be used to control AERD symptoms, not all patients diagnosed with AERD are able to complete the standard desensitization protocol. Objective: For patients who cannot complete the standard desensitization protocol, we sought to create an alternative method that allows patients to reach a therapeutic maintenance dose of aspirin. Methods: We retrospectively analyzed patients that underwent AERD desensitization, identifying 5 patients that failed the standard desensitization protocol and 6 that elected to complete the alternative aspirin desensitization. Subjects started at a dose lower than their reaction dose and subsequently increased their dosage by 40.5 mg or 81 mg every 2 to 4 weeks, with the goal of reach.. View More»
  DOI: 10.4172/2155-6121.1000207

  Abstract PDF