Journal of Nanomedicine & Nanotechnology

João Paulo Figueiró Longo

Publications

• Research Article
  Vascular Shutdown and Pro-inflammatory Cytokine Expression in Breast Cancer Tumors after Photodynamic Therapy Mediated by Nano-sized Liposomes Containing Aluminium-Chloride-Phthalocyanine
  Author(s): Maite Cevallos Mijan, João Paulo Figueiró Longo, Larissa Naves Duarte de Melo, Andreza Ribeiro Simioni, Antônio Cláudio Tedesco and Ricardo Bentes AzevedoMaite Cevallos Mijan, João Paulo Figueiró Longo, Larissa Naves Duarte de Melo, Andreza Ribeiro Simioni, Antônio Cláudio Tedesco and Ricardo Bentes Azevedo
  
  Breast cancer is the most prevalent solid tumor worldwide, being the second most common cause of death in women. Treatments recommended for breast cancer include both local and regional protocols such as surgery and radiotherapy, and systemic procedures, such as chemotherapy and hormonal therapies. In most of them, there is much functional impairment and low selectivity for tumor, leading to immunosuppression. Alternatively, some new protocols such as Photodynamic therapy (PDT) has been proposed as a therapeutic option for breast cancer management. One of the promising features related to PDT is immune activation against tumor cells. Thus, considering the importance of immunological activation against tumor cells after PDT, the aim of this study was to evaluate the expression of local and systemic inflammatory cytokines in breast cancer-bearing mice after PDT application, mediated by .. View More»
  DOI: 10.4172/2157-7439.1000218

  Abstract PDF