Clinical Microbiology: Open Access

Jiajia Zhao

Publications

• Research Article
  The Expression Level of TGF-β1, TGF-β3 and VEGF in Transplanted Oral Mucosal and Cutaneous Wounds
  Author(s): Jiarong Liu, Jiajia Zhao, Shue Li, Lijuan Zhu, Ran Yu, Yinying Qu, XiaoDan Zheng, Lin Liu and Lili ChenJiarong Liu, Jiajia Zhao, Shue Li, Lijuan Zhu, Ran Yu, Yinying Qu, XiaoDan Zheng, Lin Liu and Lili Chen
  
  Oral mucosal wounds heal faster with minimal scar compared with cutaneous wounds. In order to reduce the effect of environmental factors and find the expression difference of growth factors in oral and dermal wound, this study created the following rat wound model. The oral mucosa was firstly transplanted to left abdominal skin and after the wounds healed, a line-like full-thickness excisional wound was created on the mucosal tissue site and the right abdominal skin. Full-thickness tissue biopsies were collected from the wounds including 5 mm of the surrounding tissue at 12 hrs, 1 d, 3 ds, 5 ds and 7 ds after wounding. Quantitative real time PCR and immunohistochemistry were used to analyze the expression level of TGF-β1, TGF-β3 and VEGF. In order to find the reaction of oral and dermal fibroblasts to different growth factors, the effects of TGF-β1, TGF-β3 and VEGF.. View More»
  DOI: 10.4172/2327-5073.1000198

  Abstract PDF