Journal of Aquaculture Research & Development

Jesu Arockiaraj

Publications

• Research Article
  Poly D, L-lactide-co-glycolic Acid (PLGA)-encapsulated CpG-oligonucleotide (ODN) on Immune Response in Cyprinus carpio against Aeromonas hydrophila
  Author(s): Govintharaj Yogeshwari, Chandrasekar Jagruthi, Jesu Arockiaraj and Ramasamy HarikrishnanGovintharaj Yogeshwari, Chandrasekar Jagruthi, Jesu Arockiaraj and Ramasamy Harikrishnan
  
  The effect of Poly D, L-lactide-co-glycolic acid (PLGA) encapsulated ODN 1668 nanospheres (NS) on innate and adaptive immune response in common carp, Cyprinus carpio against Aeromonas hydrophila is reported. PLGAencapsulated ODN biodegradable NS did not have a significant impact on particle size as expected of the particles was clearly positive for non-coated and coated PLGA/ODN NS. The myeloperoxidase (MPO) activity and serum haemolysin titre significantly increased in fish injected with ODN 1668 and PLGA-encapsulated ODN 1668 groups on week 4 whereas the respiratory burst (RB) activity significantly increased when administered with ODN 1668 and PLGA-encapsulated ODN 1668 (PLGA-ODN 1668) from weeks 1 to 4. The haemoagglutinating titre was significantly enhanced in PLGA-encapsulated ODN 1668 group on week 2 while in ODN 1668 and PLGA-encapsulated ODN 1668 groups the increase manifeste.. View More»
  DOI: 10.4172/2155-9546.1000327

  Abstract PDF