Journal of Liver

Iskren Kotzev

Publications

• Research Article
  Clinical Analysis of 75 Patients with Primary Biliary Cirrhosis
  Author(s): Denitsa Dukova and Iskren Kotzev Denitsa Dukova and Iskren Kotzev
  
  Background and aims: Primary biliary cirrhosis is a chronic and slowly progressive cholestatic liver disease characterized by destruction of interlobular bile ducts, which if untreated, leads to fibrosis, cirrhosis and liver failure. It is more frequent among female patients and is usually diagnosed in the fifth decade of life. This study aims to determine the demographic, clinical, biochemical and serological characteristics and histological stage of patients with primary biliary cirrhosis. Methods: Retrospective analysis of the adult patients diagnosed with primary biliary cirrhosis at our center from January 2005 to December 2013 was performed. Data collection included demographics, clinical features, biochemical and serological markers, and histological stage. Results: 75 patients were diagnosed with primary biliary cirrhosis (mean age: 55 years, range: 19-83), of whom 92.0% were .. View More»
  DOI: 10.4172/2167-0889.1000161

  Abstract PDF