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H.M.S. Mekawey
H.M.S. Mekawey
Egypt
Publications
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Research Article
Modulating Efficiency of γ-Irradiated Rosemary in Improving the Hepatic Antioxidant Status of Ethanol Administrated Rats
Author(s): Refaat Galal Hamzaa, A. N. El Shahat and H.M.S. MekaweyRefaat Galal Hamzaa, A. N. El Shahat and H.M.S. Mekawey
Alcoholic liver disease represents a spectrum of clinical illness and morphological changes such as hepatic inflammation and necrosis (alcoholic hepatitis). Among natural antioxidants, rosemary contains several antioxidant oil and phenolic components that exhibit hepatoprotective effect. This study aimed to investigate the antioxidant effect of dietary supplementation with γ-irradiated rosemary in ethanol induced liver injury in rats. Rosemary essential oil was analyzed by gas chromatography/mass spectrometry (GC/MS). The results of biological study revealed that dietary supplementation of either raw or γ-irradiated rosemary following ethanol administration exerts remarkable modulating effect by reducing the level of total bilirubin, the activity of transaminases, gamma glutamyl transferase and serum alkaline phosphatase, decreasing the concentration of some lipid contents.. View More»
DOI: 10.4172/2161-1009.1000124