Journal of Allergy & Therapy

Hiroshi Ishii

Publications

• Research Article
  Transdermal Application of Steroid to Cervical Trachea for the Cough in Patients with Bronchial Asthma and Cough Variant Asthma-A Pilot Study
  Author(s): Mitsuhiro Kamimura, Atsuto Mouri, Kazuo Takayama, Tomonori Mizutani, Yoichiro Hamamoto, Motoyasu Iikura, Kaneyuki Furihata, Hiroshi Ishii and Kenji SugibayashiMitsuhiro Kamimura, Atsuto Mouri, Kazuo Takayama, Tomonori Mizutani, Yoichiro Hamamoto, Motoyasu Iikura, Kaneyuki Furihata, Hiroshi Ishii and Kenji Sugibayashi
  
  Background: The delivery of steroid to asthmatic patients has been limited to inhalation therapy or systemic therapy. The objective of this study was to evaluate the efficacy of transcutaneous application of steroid over the cervical trachea to asthmatic patients as an alternative route of drug delivery. Methods: Five patients with bronchial asthma (BA), 10 patients with cough-variant asthma (CVA) and 13 patients with cough predominant asthma (CPA) whose symptoms were not adequately controlled despite their current therapy were enrolled in the study. Steroid ointment of mometasone furoate or betamethasone valerate, in the amount of 1/2 fingertip unit once or twice a day for up to 3 months, to the skin over the cervical trachea, was added to the current therapy. Diphenhydramine ointment was also tried by 14 of the study participants. Results: Out of 28 patients receivin.. View More»
  DOI: 10.4172/2155-6121.1000152

  Abstract PDF