Hayato Koshino
Japan
Research Article
Key for Successful Home-Based Slow Oral Immunotherapy in Children with Egg Allergy: Age and Sensitivity
Author(s): Kyoko Sudo, Shoichiro Taniuchi, Masaya Takahashi, Kazuhiko Soejima, Yasuko Hatano, Shindo Okamoto, Keiji Nakano, Tomohiko Shimo, Hayato Koshino and Kazunari KanekoKyoko Sudo, Shoichiro Taniuchi, Masaya Takahashi, Kazuhiko Soejima, Yasuko Hatano, Shindo Okamoto, Keiji Nakano, Tomohiko Shimo, Hayato Koshino and Kazunari Kaneko
Background: Oral immunotherapy (OIT) has been recognized as a promising therapy for children with food allergy. However a part of applied patients was not able to increase doses of allergic food. Since a clear standard for the appropriate patient selection for OIT has not been established, we tried to determine the indication criteria for when and/or to whom OIT should be applied.
Method: We retrospectively reviewed the medical records of 82 children treated by home-based slow OIT which shows the administration of baked eggs orally every 2-3 days at home for two months as maintenance dose after open food challenge and statistically analyzed their clinical courses to identify the prognostic factors associated with a successful result. We applied the variables such as age, sex, symptoms during OIT, initial dose when starting OIT, specific IgE level and dislike of eggs, to a mult.. View More»
DOI:
10.4172/2155-6121.S3-009