Journal of Nanomedicine & Nanotechnology

Hai Ming Fan

Publications

• Review Article
  Multimodal Gold Nanoprobes for SERS Bioimaging
  Author(s): Vijay Raghavan, Hai Ming Fan, Peter Dockery, Antony Wheatley, Ivan Keoghx and Malini OlivoVijay Raghavan, Hai Ming Fan, Peter Dockery, Antony Wheatley, Ivan Keoghx and Malini Olivo
  
  Growing number of studies report on the improved sensitivity of various imaging modalities in detecting abnormalities within tumours. Surface enhanced Raman scattering (SERS) microscopy is a novel optical imaging technique which is advantageous in terms of greater multiplexing capability, minimal or no photobleaching of the Raman reporters, better spatial resolution and low signal-to-noise ratio within complex biological environment. For the enhancement of the Raman vibrational signal in SERS bioimaging, gold nanoparticles (GNP) are the most viable among metal nanoparticles because of comparable ease in controlling its size distribution and biocompatibility, among other parameters. GNP based SERS nanoprobes can be synthesised by tagging Raman reporter and conjugating with target specific biomolecules. Because of GNP’s wide-ranging optical properties .. View More»
  DOI: 10.4172/2157-7439.S6-002

  Abstract PDF