Journal of Aquaculture Research & Development

Gustavo Nuñez-Acuña

Publications

• Research Article
  Molecular Characterization and Transcription Analysis of P-Glycoprotein Gene from the Salmon Louse Caligus rogercresseyi
  Author(s): Valentina Valenzuela-Muñoz,Gustavo Nuñez-Acuña,Cristian Gallardo-Escárate*Valentina Valenzuela-Muñoz,Gustavo Nuñez-Acuña,Cristian Gallardo-Escárate*
  
  Despite the efforts to manage the infestation Caligus rogercresseyi on salmon species, overuse of chemical antiparasites such as avermectins, organophosphates and pyrethroids have increasingly generated drug resistance, impacting on the efficacy of salmon lice control measures. So far, previous reports have evidenced that the ATPbinding cassette transporter P-glycoprotein (Pgp) is a candidate gene implicated in the response of salmon lice to neurotoxins. However, transcription patterns of Pgp in presence of pyrethroids and the expression pattern during the ontogenetic stages are still not complete elucidated. Herein, this study characterizes the Pgp mRNA from C. rogercresseyi (Cr-Pgp) and evaluates the transcription expression in during its lifecycle, and also in adults exposed to the antiparasitic drug deltamethrin (AlphaMax). The molecular characterization of Cr-Pgp showed a comp.. View More»
  DOI: 10.4172/2155-9546.1000236

  Abstract PDF