Goyal K
Postgraduate Institute of Medical Education & Research,
Chandigarh - 160 012
India
Commentary
The Role of Helminths in Immunity
Author(s): Deepak T and Goyal K
Deepak T and Goyal K
Helminths modulate both the adaptive and innate arms of human immune system. Such immune alteration seems to have an anti-inflammatory effect. Chronic helminth infections switch the immune response from Th1 to Th2 by various mechanisms and by different helminth derived molecules. Though these immunological responses provide a survival advantage, they seem to hamper the response to non-helminth derived antigens. Immune response to oral vaccines and many auto-immune disorders are influenced by immunomodulatory effects of helminths. As a part of eukaryotic community in the gut, helminths might have a potential role in the development of immune system.
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DOI:
10.4172/2155-6121.1000231