Journal of Allergy & Therapy

Gemma Mencia

Publications

• Case Report
  Induction of Tolerance to Clopidogrel in a Patient with Ischemic Cardiopathy
  Author(s): David El-Qutob, Gemma Mencia and Maria Jose BoschDavid El-Qutob, Gemma Mencia and Maria Jose Bosch
  
  Patients with acute coronary syndrome (ACS) that are admitted in the emergency room are treated with AAS and a loading dose of clopidogrel (300-600 mg) unless contraindicated. A 47 year old male was admitted in the cardiology ward with the diagnosis of ACS. He was revascularized with two drug eluting stents. A loading dose of 300 mg of clopidogrel was used and a 12 months period with dual antiplatelet therapy was recommended (AAS 100 mg plus clopidogrel 75 mg per day). After seven days taking clopidogrel and AAS, the patient presented non-immediate erythematous, pruritic, maculopapular rash. He tolerated AAS after skin reaction. The patient was referred to our department by the cardiology service to perform an induction of tolerance to clopidogrel. There are several, outpatient and inpatient, protocols of desensitization to clopidogrel usually in one day, all of them with good results.. View More»
  DOI: 10.4172/2155-6121.1000144

  Abstract PDF