Gamal M Mosaad
Egypt
Research Article
Immunomodulation of Nile Tilapia, Oreochromis niloticus, by Nigella sativa and Bacillus subtilis
Author(s): Ahmad A Elkamel *,Gamal M Mosaad
Ahmad A Elkamel *,Gamal M Mosaad
The aim of this study is to investigate the modulation of the immune system of Nile tilapia, Oreochromis niloticus,by the black cumin seeds, Nigella sativa, or Bacillus subtilis PB6 (CloSTAT) as feed additives. Four diet regimes, a basic (control), CloSTAT, nigella, or combination of the black cumin seeds and CloSTAT were formulated and used to feed fish for 30 successive days. Half of the fish were used to investigate some of the immune parameters as serum globulins, white blood cell counts, and phagocytic activities and phagocytic indices. The other half of fish was subjected to infection challenge with Aeromonas hydrophila to investigate the disease resistance ability of the fish received the feeding additives. Results showed that the serum globulins have significantly increased in fish received the combination diet, while white blood cells have si.. View More»
DOI:
10.4172/2155-9546.1000147