Gadadhar Dash
India
Research Article
Histopathology and Wound Healing in Oxytetracycline Treated Oreochromis niloticus (L.) Against Aeromonas hydrophila Intramuscular Challenge
Author(s): Julinta RB, Abraham TJ, Anwesha Roy, Jasmine Singha, Gadadhar Dash, Nagesh TS and Patil PK
Julinta RB, Abraham TJ, Anwesha Roy, Jasmine Singha, Gadadhar Dash, Nagesh TS and Patil PK
Antibiotics are very important tools for the control of fish bacterial diseases. Yet, there are strict regulations controlling the use of antibiotics in aquaculture. This study assessed the efficacy oxytetracycline dihydrate (OTC) at a dose of 2 g, 4 g, 6 g and 8 g/100 pounds fish/day against Aeromonas hydrophila challenge in Nile tilapia Oreochromis niloticus as well as the histopathological alterations in kidney and muscle, and wound healing. The commercial pellet feed was top dressed with OTC using 5 ml vegetable oil as a binder. The fish were injected intramuscularly with A. hydrophila at ≈1 × 108 cells/fish and then fed OTC feeds at 2% of their body weight for 10 days. The fish fed with 8g OTC/100 pounds fish/day recorded the lowest mortality (3.33%). The untreated fish recorded 8.33% mortality. Histologically, the kidney tissues of O. n.. View More»
DOI:
10.4172/2155-9546.1000488