Biochemistry & Analytical Biochemistry

Frieder W. Scheller

Publications

• Editorial
  Bio vs. Mimetics in Bioanalysis: An Editorial
  Author(s): Frieder W. Scheller and Aysu Yarman Frieder W. Scheller and Aysu Yarman
  
  Natural evolution has created biopolymers on the basis of amino acids and nucleotides showing high chemical selectivity and catalytic power. Molecular recognition by antibodies and catalytic conversion of the substrate molecules by enzymes take place in so called paratopes or catalytic centres of the macromolecule which comprise typically 10-15 amino acids. The concerted interaction between the reaction partners result in affinities down to nanomolar concentrations for the antigen binding and approaches one million turnovers per second in enzyme-catalyzed reactions. .. View More»
  DOI: 10.4172/2161-1009.1000e154

  Abstract PDF