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Ferreira NVS
Ferreira NVS
Brazil
Publications
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Research Article
QuantiFERON®-TB gold in-tube is not Useful for Diagnosing Active Tuberculosis in HIV/AIDS Patients with Severe Immunodeficiency: Results from Brazil
Author(s): Giselle Burlamaqui Klautau, Bammann RH, Ferreira NVS, Afiune JB, Burattini MN and Rodrigues DSGiselle Burlamaqui Klautau, Bammann RH, Ferreira NVS, Afiune JB, Burattini MN and Rodrigues DS
Purpose: To assess interferon gamma release assay (IGRA) and tuberculin skin test (TST) performances in the diagnosis of active tuberculosis (TB) in adults with HIV/AIDS with different degrees of immunodeficiency. Methods: Cross-sectional study conducted with 90 HIV/TB-coinfected adults, São Paulo, Brazil. TB diagnosis was established based on the presence of positive sputum smear, culture, or anatomic-pathological examination. The participants responded to a questionnaire and were submitted to physical examination, chest x-ray (CRX), serum CD4+ and CD8+ T cell count, TST, and IGRA (QuantiFERON®-TB Gold In Tube, Cellestis, Carnegie, Australia). Results: Characteristics of 90 HIV/TB-coinfected individuals: male (60.0%), white (54.4%), single (57.3%), and average age 39 (±10.8) years with pulmonary TB (45... View More»
DOI: 10.4172/2329-891X.1000150