Fatima AI Al-Khodir
Princess Nora Bint Abdul Rahman University,
Saudi Arabia
Research Article
Synthesis, Spectroscopic and Biologically Assessments of Calcium(II), Zinc(II), Palladium(II) and Gold(III) Sulfacetamide Sodium Complexes: Gold(III) Nano Medical Complex as an Anticancer Agent
Author(s): Fatima AI Al-Khodir
Fatima AI Al-Khodir
The preparation of metal-sulfa drug complexes has an important topic due to their biological applications as chemotherapeutic agents against bacterial infections in microorganism. This paper report the synthesis, characterization and antimicrobial screening of synthesized Ca(II), Zn(II), Pd(II) and Au(II) sulfacetamide sodium (SAM-Na) drug complexes. These complexes were assigned based on elemental analyses, molar conductance and some of essential spectral techniques like IR, 1H-NMR, and electronic spectroscopy. These analyses prove that the sulfacetamide sodium salt was reacted with Ca(II), Zn(II) and Pd(II) metal ions as a bidentate ligand through both oxygen atoms of acetamide and sulfonyl groups. On contrary, the SAM-Na acts as a monodentate ligand through its –NH2 amino in case of gold(III) complex. These complexes were pla.. View More»
DOI:
10.4172/2157-7439.1000326