Farya Zafar
Pakistan
Review Article
NSAIDs; Safety and Risk Assessment in CVS Events, Comparisons and
Facts
Author(s): Hina Hasnain, Huma Ali, Anum Tariq, Farya Zafar and Safila NaveedHina Hasnain, Huma Ali, Anum Tariq, Farya Zafar and Safila Naveed
Products of Non-steroidal anti-inflammatory drugs (NSAIDs) are principally and most widely utilized due to their multipurpose actions, i.e., analgesic anti pyretic and anti-inflammatory effect. Beside their therapeutic effect their toxic effect based on their selectivity of cyclooxygenase (COX) enzyme. While cardiovascular toxicities associated with NSAIDs are mainly related with COX-2 selective inhibitor and primarily dependent on their dose time and duration. Variability in therapeutic response and susceptibility to toxicity is well recognized and can be manageable if considerable precautions implement. .. View More»
DOI:
10.4172/jbb.1000273