Journal of Microbial & Biochemical Technology

Fareed SM Hassan

Publications

• Research Article
  Process Optimization of L-Glutaminase Production; a Tumour Inhibitor from Marine Endophytic Isolate Aspergillus sp. ALAA-2000
  Author(s): Mervat Morsy Abbas Ahmed, Taher M Taha, Nageh F Abo-Dahab and Fareed SM HassanMervat Morsy Abbas Ahmed, Taher M Taha, Nageh F Abo-Dahab and Fareed SM Hassan
  
  L-Glutaminases have received significant attention recently owing to their potential applications. All endophytic fungi recovered from the marine soft sponge Aplysina fistularis were able to produce L-glutaminase. During screening program, Aspergillus sp. ALAA-2000 showed the highest L-glutaminase production levels. The production of L-glutaminase by Aspergillus sp. ALAA-2000 was evaluated under different fermentation modes and parameters. The L-glutaminase synthesis was increased their yield after the optimization of fermentation parameters. The hot water 40°C was the best leaching agent extracted of soy bean for L-glutaminase production (21.89 U/ml) under solid state fermentation (SSF). The highest L-glutaminase activity (91.92 U/ml) was achieved after two days incubation period under submerged fermentation (SmF). L-glutamine, dextrose, cysteine and Magnesium chloride supported .. View More»
  DOI: 10.4172/1948-5948.1000313

  Abstract PDF