Eva Chamorro
Facultad de Óptica, Optometría y Visión,
Universidad Complutense de Madrid. C/ Arcos de Jalón, 118. 28037. Madrid
Spain
Research Article
Photoprotective Effects of Blue Light Absorbing Filter against LED Light Exposure on Human Retinal Pigment Epithelial Cells In Vitro
Author(s): Eva Chamorro, Sergio F Carralero, Cristina Bonnin-Arias, María Jesús Pérez-Carrasco, Javier Muñoz de Luna, Daniel Vázquez Ing and Celia Sánchez-RamosEva Chamorro, Sergio F Carralero, Cristina Bonnin-Arias, María Jesús Pérez-Carrasco, Javier Muñoz de Luna, Daniel Vázquez Ing and Celia Sánchez-Ramos
Abstract
Background: Over the recent years, several researches have speculated about the effects of Light Emitting
Diodes (LEDs) radiation on retinal epithelium cells (RPE). Worldwide, most people live exposed to LEDs irradiation
incorporated in screens of PCs, phones and TV sets. These lights give rise to the formation of reactive oxygen
species and induce mutagenic mechanisms which lead to apoptosis and consequently to degenerative eye diseases,
such as age-related macular degeneration (AMD). Thus, it is a priority interest to develop appropriate solutions for
the growing industry field of LED light phototoxicity. The aim of this study was to investigate the protective effects of
blue light absorbing filters in order to decrease induced apoptosis on human retinal pigment epithelial cells.
Methods: Human retinal pigment epithelial cells were exposed to 3 light-darkness (12 hours.. View More»
DOI:
10.4172/2157-2518.S6-008