Journal of Blood Disorders & Transfusion

Esraa Hezam

Publications

• Research Article
  Prevalence and Trends of HBV, HCV, and HIV Serological and NAT Markers and Profiles in Saudi Blood Donors
  Author(s): Wafa M Elbjeirami, Nidal M Arsheed, Hanadi M Al-Jedani, Noha Elnagdy, Hazem M Abou Eisha, Amal Abdulwahab, Nahla AB Abdulateef, Esraa Hezam and Faisal A Al-AllafWafa M Elbjeirami, Nidal M Arsheed, Hanadi M Al-Jedani, Noha Elnagdy, Hazem M Abou Eisha, Amal Abdulwahab, Nahla AB Abdulateef, Esraa Hezam and Faisal A Al-Allaf
  
  Background: Epidemiologic studies on the prevalence of transfusion-transmitted infections (TTIs) in Saudi Arabia (SA) regions are limited. This study investigated prevalence of HBV, HCV, and HIV using both serological and nucleic acid testing (NAT) methods to determine temporal and geographic trends among blood donors in Makkah. Our secondary objective was to realize the most suitable NAT format, without compromising sensitivity of NAT results by using individualized or mini-pool testing. Methods: Serologic and NAT screening records of 22,963 blood donors from January 2011 to December 2014 were evaluated for HBsAg, Anti-HBc, Anti-HCV, Anti-HIV, HBV-DNA, HCV-RNA, and HIV-RNA. Prevalence rates were calculated for TTIs per hundred donations and additional analysis was conducted to examine donor profiles associated with positive serologic and NAT .. View More»
  DOI: 10.4172/2155-9864.1000280

  Abstract PDF