Esayes Taddese Gebremariam
Ethiopia
Review Article
Stem Cell Therapy for Myocardial Infarction: Challenges and Prospects
Author(s): Gizaw Dabessa Satessa, Jima Likisa Lenjisa, Esayes Taddese Gebremariam and Minyahil Alebachew Woldu
Gizaw Dabessa Satessa, Jima Likisa Lenjisa, Esayes Taddese Gebremariam and Minyahil Alebachew Woldu
Myocardial infarction causes death worldwide with the greatest incidence being in the United States. Although there have been many advances in myocardial re-perfusion strategies and novel pharmacological approaches, therapies for treating acute and chronic myocardial ischemic damage remain limited. This means that no currently available heart failure treatment has demonstrated an ability to generate new muscle tissue within the scared regions of the heart. Stem cell, however, offers new hope to patients who have otherwise limited choices. Therefore, this review aims at exploring the use and peculiarities of stem cell therapy for myocardial infarction. But the success of stem cell therapy for clinical use needs the validation of several issues ranging from selection of appropriate stem cells, routes of transfer, establishment of conducive trans-differentiation milieu with associated cy.. View More»
DOI:
10.4172/2157-7633.1000270