Emmanuel K Uko
Nigeria
Special Issue Article
Uncommon Rh Phenotypes in a Cross Section of Nigerian Antenatal Women: Implications for Molecular Genotyping of Blood Groups
Author(s): Zaccheaus A Jeremiah, Amos A Biribo, Teddy C Adias and Emmanuel K Uko
Zaccheaus A Jeremiah, Amos A Biribo, Teddy C Adias and Emmanuel K Uko
Background: This study aimed to determine the frequency of rare blood group antigens among pregnant women in Port Harcourt Metropolis.
Methods: The frequencies of Rh antigens and phenotypes of the pregnant women in Port Harcourt Metropolis, Nigeria, were determined, using standard serologic techniques.
Results: Of the 374 pregnant women studied, the frequencies of the Rh antigens within the population were D (89.0%), c (82.0%), e (54.0%), C (24.3%), E (20.1%). The frequencies of the Rh antithetical antigens were DD/Dd (91.2 %), Cc (19,5%), cc (84.5%), Ee (13.9%), ee (54.3%), CC (25.1%), EE (19.8%) and dd (10.4%). Seven (1.9%) were found to be Rhnull, sixteen(4.3%) were found to be D-- or exalted D. Phenotypes without RhD reactivity were –c- (2.9%), - Cc (0.3%), -C- (0.3%), -Ee (0.5%) and –E- (0.3%). The most frequently occurring Rh phenotype was Dccee with a .. View More»
DOI:
10.4172/2155-9864.S10-001