Edward Szłyk
Poland
Research Article
Application of Capillary Isotachophoresis in Phenothiazines Determination
Author(s): Marzanna Kurzawa, Anna Filipiak-Szok, Aneta Jastrzębska and Edward SzłykMarzanna Kurzawa, Anna Filipiak-Szok, Aneta Jastrzębska and Edward Szłyk
A capillary isotachophoretic method (cITP) using three electrolyte systems for determination of promethazine, thioridazine and chlorpromazine hydrochlorides in pharmaceutical preparations was demonstrated. Proposed systems were characterised by linearity range 5-100 mg/L with R2 in all cases were higher than 0.999. The elaborated method was tested on pharmaceutical preparations. The recovery values were from 96.5% to 101.3%. The proposed isotachophoretic method is simple with acceptable precision and accuracy and can be suitable for routine analysis of studied biological active compounds. .. View More»
DOI:
10.4172/2153-2435.1000173