Biology and Medicine

Desak Made Wihandani

Publications

• Research Article
  Topical Binahong (Anredera cordifolia) Leaf Extract Increases Interleukin-6 and VEGF (Vascular Endothelial Growth Factor) during Burn Wound Healing in Wistar Rats Infected with Pseudomonas aeruginosa
  Author(s): Dewa Made Sukrama, Desak Made Wihandani and Amertha Putra ManuabaDewa Made Sukrama, Desak Made Wihandani and Amertha Putra Manuaba
  
  Burn injuries still remain a major problem. It leads to nosocomial infection by Pseudomonas aeruginosa, the most common bacteria that infects burn injuries, due to its long duration of hospitalization. Previous research found that the extract of Anredera cordifolia, locally known as “binahong” in Indonesia, is effective in burns healing. Interleukin-6 (IL-6) and VEGF are substances that are important in healing process. This study aims to determine how topical Anredera cordifolia leaf extract accelerates burn wound healing, increases IL-6 level, and increases VEGF production in rats with Pseudomonas aeruginosa-infected burn injuries. This is an experimental study with the Posttest Only Control Group Design, involving a total of 32 samples of wistar rats with infected burn wounds. The treatment group received 2 ml of the topical extract of Anredera Cordifolia leaf while the.. View More»
  DOI: 10.4172/0974-8369.1000369

  Abstract PDF