Cardiovascular Pharmacology: Open Access

De Waele S

Publications

• Research Article
  The Link between Early Biomarker Analysis and the Neurological Outcome in Stroke Patients
  Author(s): De Waele S and Hachimi-Idrissi S* De Waele S and Hachimi-Idrissi S*
  
  Stroke patients have an uncertain prognosis. It has been postulated that biomarkers’ concentrations upon admission could be linked to the neurological outcome. This meta-analysis reviewed the literature and collected data for 65 biomarkers. To increase power of evidence, only biomarkers who were: • Significant in the meta-analysis, • Reported by two or more studies conducted by different authors, • Displaying more than 300 patients and • Displaying less or equal to 60% heterogeneity were retained. Eight biomarkers were found to be relevant; TNFα, white blood cell count, non-fasting glucose, GPT, D-dimer, fT3, cortisol and MRproANP. These except for GPT and fT3 show the same trend: a low concentration at admission is linked to a good outcome. For GPT and fT3 the reverse was observed; a low concentration i.. View More»
  DOI: 10.4172/2329-6607.1000219

  Abstract PDF