Dawud Al-Eisawi
Jordan
Research Article
Cytotoxic Effect of Selected Wild Medicinal Plant Species from Jordan on Two Different Breast Cancer Cell Lines, MCF7 and T47D
Author(s): Israa Yousef, Sawan Oran, Yasser Bustanji, Dawud Al-Eisawi and Bashaer Abu-IrmailehIsraa Yousef, Sawan Oran, Yasser Bustanji, Dawud Al-Eisawi and Bashaer Abu-Irmaileh
Background: Breast cancer is the most common type of cancer in females in Jordan, it accounts for about 35.3% of all female cancers. Searching for alternative medicine from plants for breast cancer is a paramount importance. No studies have investigated the cytotoxic effect of the plants of Ajuga chia, Micromeria nervosa and Origanum dayi that are belonging to the family Lamiaceae and are growing wild in Jordan.
Objective: To investigate the cytotoxic effect of the A. chia, M. nervosa and O. dayi plant species against two different breast cancer cell lines MCF7 and T47D.
Materials and methods: The aerial parts of the aforementioned plant species were extracted with water and ethanol. Cell viability was assessed using MTT assay, after incubation with various concentrations of plant extracts.
Result.. View More»
DOI:
10.4172/0974-8369.1000443