Daniel Wilfred
Ghana
Research Article
CKD-EPI is a Better Tool for Detecting Renal Dysfunction in Hypertensive Pregnancy: A Case-Control Study in Ghana
Author(s): Linda Ahenkorah Fondjo, Owiredu WKBA, Samuel Asamoah Sakyi, Christian Obirikorang, Daniel Wilfred and Richard KD EphraimLinda Ahenkorah Fondjo, Owiredu WKBA, Samuel Asamoah Sakyi, Christian Obirikorang, Daniel Wilfred and Richard KD Ephraim
Background: Pregnant women with hypertension are at an increased risk of renal impairment. This study assessed the use of CKD-EPI and 4v-MDRD for early diagnosis of renal impairment in pregnant women with hypertension. Methods: This case-control study was conducted at Suntreso Government Hospital Kumasi, Ghana. In all, 220 pregnant women were recruited, 84 had Gestational Hypertension, 36 had Preeclampsia, with 100 normotensive pregnant women as controls. Structured Questionnaires were used to obtain socio-demographic and clinical information. 4 mL of venous blood was collected for estimation of electrolytes, urea, creatinine and uric acid; urine was collected for estimation of protein using dipstick. The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) and Modification of Diet in Renal Disease (MDRD-4) equations were used to assess and classify renal impairments. Results: .. View More»
DOI:
10.4172/2329-6925.1000361