Journal of Liver

Dan Chen

Publications

• Research Article
  Effects of Ginseng Polysaccharides on Hepatocellular Energy Metabolism in Hepatic Ischemia Reperfusion Injury in Rabbits
  Author(s): Haie Chen, Yingchun Ma, Lei Ying, Dan Chen, Yakun Liu, Shan Zhao, Guanlong Li and Wantie Wang Haie Chen, Yingchun Ma, Lei Ying, Dan Chen, Yakun Liu, Shan Zhao, Guanlong Li and Wantie Wang
  
  Objective: To investigate the effects of ginseng polysaccharides on hepatocellular energy metabolism in Hepatic Ischemia reperfusion injury of rabbits. Methods: 30 rabbits were randomly divided into 3 groups: Control Group (C), Ischemia-Reperfusion Injury Group (IR) and Ginseng Polysaccharides Group (GP). We investigated Alanine Aminotransferase (ALT) in plasma, Adenosine Triphosphate (ATP), Adenosine Diphosphate (ADP), Adenosine Monphosphate (AMP), Total Adenylic Acid Number (TAN), and Energy Charge (EC) in liver and morphological changes of hepatic cells. Results: In group IR, the content of ATP and EC in hepatic tissue were obviously less than those of group C (P<0.01). The content of ADP and AMP was more abundant than those of group C (P<0.01). In both groups there was little or no significant content of TAN (P>0.05), and was obviously morphological ab.. View More»
  DOI: 10.4172/2167-0889.1000107

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