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Corpuz MJT
Corpuz MJT
Philippines
Publications
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Research Article
Platelet and Leukocyte Increasing Effects of Syzygium cumini (L.) Skeels (Myrtaceae) Leaves in a Murine Model
Author(s): Bandiola TMB and Corpuz MJT Bandiola TMB and Corpuz MJT
Context: Syzygium cumini (L.) Skeels (Myrtaceae) is popularly known to have various pharmacological and traditional uses. Prior to this study, there were no claims reporting its potential use for dengue by increasing platelet and leukocyte levels. Objectives: The effects of the methanolic extract of S. cumini leaves on the platelet and leukocyte levels were evaluated in Sprague-Dawley rats at doses 400 mg/kg and 800 mg/kg body weight. Methodology: The bioassay utilized 24 rats that were divided into four groups (n=6) where hydroxyurea was used to induce depletion of platelet and and leukocyte levels in all groups. After induction, oral treatment of methanolic extract was given daily to the treatment groups for six days. The platelet and leukocyte counts were measured before induction to get the baseline, after i.. View More»
DOI: 10.4172/2153-2435.1000586