Journal of Microbial & Biochemical Technology

Colet Nyakunu

Publications

• Research Article
  The Effect of Selected Combretum Species from Zimbabwe on the Growth and Drug Efflux Systems of Mycobacterium aurum and Mycobacterium smegmatis
  Author(s): Ruvimbo Magwenzi, Colet Nyakunu and Stanley MukanganyamaRuvimbo Magwenzi, Colet Nyakunu and Stanley Mukanganyama
  
  Treatment of tuberculosis has become a challenge due to the rapid increase of multidrug and extensive drug resistant Mycobacterium tuberculosis. Medicinal plants might represent a possible source for new potent antibacterials to which pathogen strains are not resistant. In this study, five Combretum plant species-Combretum imberbe, Combretum zeyheri, Combretum hereroense, Combretum elaeagnoides and Combretum platypetalum used in traditional medicine were exposed to susceptibility tests to determine the effects of drug accumulation in avirulent M. smegmatis and M. aurum. The MIC values of the potent plant species was then determined. Using the agar disc diffusion assay, it was found out that the only the ethanolic extract from Combretum imberbe was active on M. smegmatis and it had an MIC of 125 μg/ml in the broth microdilution assay. However, using Sabouraud dextrose broth, Combret.. View More»
  DOI: 10.4172/1948-5948.S3-003

  Abstract PDF