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Cole C
Cole C
Tanzania
Publications
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Research Article
Comparison of Antimicrobial and Wound Healing Agents on Oral Fibroblast Viability and In-vivo Bacterial Load
Author(s): Bowen J*,Cole C,McGlennen R Bowen J*,Cole C,McGlennen R
Oral rinses are designed to restore healing (often for mouth sores) or kill oral bacteria. The balance between bactericidal and restorative effects is not often achieved, leading to unwanted side effects of the products. In this study we ran comparisons of currently available cleansing rinses, measuring possible toxic effects on gingival fibroblasts invitro and their bactericidal effects in-vivo. The commercial products tested included oral rinses based on: chlorhexidine gluconate, carbamide peroxide,aloe vera, essential oils (with and without alcohol) and a combination product with essential oils and carbamide peroxide. All products except the combination rinse caused 100% gingival fibroblast cell (HGF-1) death after a single 30 second rinse. In addition, the same products increased the cytotoxic effects of a chemotherapeutic even at.. View More»
DOI: 10.4172/2161-1122.1000305