Journal of Blood Disorders & Transfusion

Chinonso AY

Publications

• Case Series
  Red Cell Exchange Transfusion in Sickle Cell Anaemia Patients at the University College Hospital, Ibadan, Nigeria
  Author(s): Akingbola T, Fasola F, Khadijat AS, Alonge T, Chinonso AY Akingbola T, Fasola F, Khadijat AS, Alonge T, Chinonso AY
  
  Introduction: The prohibitive cost of Haemopoietic Stem Cell Transplant (HSCT) makes many Nigerians with sickle cell anaemia (SCA) dependent on supportive therapies. Red cell exchange (RCE) transfusion (erythrocytaphersis) provides an effective means of improving the oxygen carrying capacity of the patient’s red blood cells, reduces blood viscosity, sickled cells and prevents vaso-occlusive and hemolytic complications of SCA. We present three case reports of automated RCE highlighting benefits and potential risks observed following the procedure. Methods: The COBE® Spectra™ version 6.1, which operates by separating blood into its component parts by centrifugation, allowing segmentation by specific gravity, was utilized to conduct automated therapeutic erythrocytapheresis on patients with SCA in this centre. Indications were recu.. View More»
  DOI: 10.4172/2155-9864.1000396

  Abstract PDF