Chatterjee T
Suraksha Genomics (R & D Division of Suraksha Diagnostic),
DD-18/1. Sector 1, Salt Lake, Kolkata-700064, West Bengal
India
Commentary
Predictive and Prognostic Factors in Breast Cancer and their Association with ER PR HER2/neu Expression
Author(s): Sinha S, Nath J, Mukherjee A and Chatterjee T
Sinha S, Nath J, Mukherjee A and Chatterjee T
Background: Breast Cancer is the most common malignancy amongst Indian women. Adjuvant therapy, which helps in prolonging survival, is determined by the expression of Estrogen Receptor (ER), Progesterone Receptor (PR) and Human Epidermal Receptor (HER2/neu) on the cancer cells. Expression of these receptors is governed by some patient and tumor characteristics. Aims and objectives: The aim of this study is to look into the association of patient age, tumor grade and lymph node stage with ER PR HER2/neu expression. Materials and methods: The study was conducted in the Department of Pathology of Suraksha Diagnostics for a period of two years (2014-2016). The sample size is 68. For all specimens of breast cancer received by modified radical mastectomy, patient age, tumor histological grade as per Nottingham’s Histological score and lymph node stage were recorded and correlated with.. View More»
DOI:
10.4172/2157-2518.1000263