Pharmaceutica Analytica Acta

Cécile Cren-Olivé

Publications

• Research Article
  Comparison of Two Analytical Methods for the Determination of Traces of Veterinary Antibiotics and Steroid Hormones in Soil Based on Pressurised Liquid Extraction (PLE) and Quick, Easy, Cheap, Effective, Rugged, Safe (Modified-Quechers) Extraction
  Author(s): Marie-Virginie Salvia, Cécile Cren-Olivé, Laure Wiest, Robert Baudot and Emmanuelle Vulliet Marie-Virginie Salvia, Cécile Cren-Olivé, Laure Wiest, Robert Baudot and Emmanuelle Vulliet
  
  Veterinary antibiotics and steroid hormones can be present at low levels in soil. Analytical methodologies are therefore necessary to analyse these compounds at the trace level in such a complex matrix. The goal of this work was to compare Pressurised Liquid Extraction (PLE), which is usually used to extract drugs from soil, and a modified-QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) method. Furthermore, several clean-up methods were evaluated. Selective Pressurised Liquid Extraction (SPLE) and Dispersive Solid Phase Extraction (dSPE) used after PLE and QuEChERS, respectively, were tested. These techniques permit a fast and simple purification step. SPE, which is frequently used, was also evaluated. To perform this comparison, both recoveries and matrix effects were compared and the analyses were performed using liquid chromatography coupled to tandem mass spectrometry (LC-.. View More»
  DOI: 10.4172/2153-2435.1000315

  Abstract PDF