Journal of Blood Disorders & Transfusion

Brown Holy

Publications

• Research Article
  The Preterm Effect of Antiretroviral Drugs on Total Lymphocyte Cells and CD4 Cells in HIV-Infected Pregnant Women
  Author(s): Okeke Chukwubike Udoka, Ukibe Solomon Nwabueze, Holy Brown and Ezeiruaku Ferdinand Okeke Chukwubike Udoka, Ukibe Solomon Nwabueze, Holy Brown and Ezeiruaku Ferdinand
  
  Background: HIV infected pregnant women are placed on antiretroviral drugs for treatment and to avoid maternal to child transmission of HIV. This study was carried out to investigate the effects of the antiretroviral drugs (ARD) on CD4 and Total Lymphocyte cell count (TLC) among these women. Method: A total of 120 women participated in this study at Bori General Hospital Nigeria. Sixty (60) of them were seropositive to HIV while 60 were seronegative. Blood sample was collected from both groups of women at 2nd and 3rd trimester. The seropositve group was placed on ARD (Nevirapine, Zidovudine) after initial collection of sample at 2 nd trimester. CD4 count and TLC were estimated in these samples using Cyflow machine and manual method respectively. Result: CD4 count and TLC were significantly (p < 0.05) reduced in .. View More»
  DOI: 10.4172/2155-9864.1000353

  Abstract PDF