Bedaso Kebede
Veterinary Drug and Animal Feed Administration and Control Authority,
31303 Addis Ababa
Ethiopia
Research Article
A Study on the Effect of Monomorphic Trypanosoma brucei rhodesiense, (Eatro 3 ET at 1.2) on Experimentally Infected Goats and Swiss White Mice
Author(s): Hailisha Gudisa, Bedaso Kebede, Getachew Terefe and Dereje Tsegaye
Hailisha Gudisa, Bedaso Kebede, Getachew Terefe and Dereje Tsegaye
study was done to assess the effect of Trypanosome brucei rhodesiense on experimentally infected goats and mice to see the effect of the study parasite and to determine the minimum dose that should be used to establish chronic infection. Three goats, identified with number as 908, 713, and 907, received 106, 5 × 104, and 103, parasite in dose volume of 0.5 ml intravenously, respectively. All infected goat showed clinical sign of trypanosomosis. Number 908 was died on 55th day post infection with PCV of 24%. A total of 11 Swiss white mice were also infected to study the effect of the study parasite. A total of 6 mice were infected in the first round (firsts batch), with 1x103 parasites in 0.3 ml dose volume, ip. All mice died before the 5th day post infection. There was no significant change in PCV and body weight almost in all infected mice during the course of infection. A tota.. View More»
DOI:
10.4172/2155-9597.1000287