Beatrice Moore-Igwe
Nigeria
Research Article
Storage Related Haematological and Biochemical Changes of CPDA-1 Whole Blood in a Resource Limited Setting
Author(s): Teddy C Adias, Beatrice Moore-Igwe and Zaccheaus A Jeremiah
Teddy C Adias, Beatrice Moore-Igwe and Zaccheaus A Jeremiah
Majority of the blood banks in Nigeria still practice whole blood banking. The changes associated with the storage of blood in our blood banks have not been reported. This study was aimed at bridging this gap. Blood (450 ml) was drawn from ten healthy volunteer donors into CPDA-1 anticoagulant and placed on the quarantine shelf of the blood bank refrigerator maintained at 2-8°C. Blood bags were screened for HCV, HBsAg, Syphilis and HIV 1&2 and were confirmed negative. Samples were collected at 1, 7, 14, 21 and 28 days and tested for hematological and biochemical using the PE-600 fully auto Haematology analyzer (China) for hematological parameters, Excite -40 ESR analyzer and Prestige 24i automated clinical analyzer for biochemical parameters. Comparison of day 1 versus day 7 revealed that the granulocytes were drastically reduced from 1.93 × 109 /L on day 1 to 0.33 &time.. View More»
DOI:
10.4172/2155-9864.1000124