Journal of Blood Disorders & Transfusion

Audu I

Publications

• Research Article
  Evaluation of Trace Elements in Adult Sickle Cell Anaemia Patients in Zaria, North Western Nigeria
  Author(s): Garba N, Ifeanyichukwu OM, Amilo GI and Audu IGarba N, Ifeanyichukwu OM, Amilo GI and Audu I
  
  Sickle cell anemia is a genetic disorder that is caused due to the inheritance of a mutant gene that encodes haemoglobin S (HbS). The amino acid glutamic acid is replaced with valine in the sixth position of b-globin chain. Protection of red cell membrane from free radical mediated oxidative stress is crucial to the management of SCD. Trace elements such as Copper, Zinc and Magnesium are of great benefit towards relieve of oxidative stress associated with red blood cell membranes. This study was carried out to evaluate some trace elements in adult sickle cell anaemia patientsattending sickle cell clinic, ABUTH-Zaria. Ethical clearance was obtained from ethics committee of Ahmadu Bello University Hospital Zaria, questionnaires were administered and informed consent was obtained from patients or their parents. One hundred and one (101) subjects aged 18 to 46 years participated in this s.. View More»
  DOI: 10.4172/2155-9864.1000347

  Abstract PDF