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Assila Hadj Ali
Assila Hadj Ali
Laboratory of Cytogenetic, Molecular Genetics and Human Reproductive Biology, CHU Farhat Hached,
Sousse
Tunisia
Publications
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Research Article
Evaluation of Seminal Plasma Antioxidants and Serum Male Hormones Status in Infertile Patients with Unbalanced Chromosomal Abnormalities
Author(s): Assila Hadj Ali, Meriem Mahdi, Tesnim Ajina, Ali Saad and Habib Ben AliAssila Hadj Ali, Meriem Mahdi, Tesnim Ajina, Ali Saad and Habib Ben Ali
Background: Male infertility appears to be a major clinical problem among men of reproductive age in all societies. Idiopathic male infertility is considered to be a multifactorial disorder affected by genetic, environmental, and hormonal factors. Oxidative stress seems to stand out as one of the underlying mechanisms. In this context, we aimed to evaluate seminal plasma antioxidants SOD (superoxide dismutase), GPx (glutathione peroxidase), CAT (catalase) and zinc levels, hormone levels, and semen parameters in fertile donors and patients with unbalanced chromosomal abnormalities.Methods: Semen samples from 119 patients with unbalanced chromosomal abnormalities and 30 fertile men were analyzed according to World Health Organization guidelines (2010). All patients underwent a measurement of testosterone (T), follicle-stimulating hormone (FSH) and.. View More»
DOI: 10.4172/0974-8369.1000429