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Anurag Payasi
Anurag Payasi
Venus Medicine Research Centre, Hill Top Industrial Estate, Bhatoli, Kalan, Baddi, H.P. - 173205,
India
Publications
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Research Article
Battling the Methicillin-Resistant Staphylococcus aureus Biofilm Challenge with Vancoplus
Author(s): Manu Chaudhary and Anurag PayasiManu Chaudhary and Anurag Payasi
The present study was conducted with the aim to find the prevalence of biofilm formation ability among methicillin resistant Staphylococcus aureus (MRSA) isolates and to assess the activities of commonly used drugs against biofilm producing MRSA. Evaluation of prevalence of genes involved in MRSA biofilm production and their gene expression was also studied. Of 55 MRSA, 47 isolates were biofilm producers and 8 isolates were non-biofilm producers. Of 47 biofilm producers, 24 (51.0%), 14 (29.8%) and 9 (19.1%) produced strong (OD570 ≥ 0.5), medium (OD570 ≥ 0.2 to <0.5), weak (OD570 0 to <0.2) biofilm, respectively. Of the 47 isolates, eight determinants (genes) (eno, hla, hlb, clfA, fnaA, icaA, agrII and sar) were found predominantly among 70 to 80% isolates whereas cna was observed only in 21.3%, finbB in 10.6% and ebps in 32% isolates. Amongst the strong biofilm producers (.. View More»
DOI: 10.4172/1948-5948.S10-001