PMC/PubMed Indexed Articles
Indexed In
- Open J Gate
- Genamics JournalSeek
- Academic Keys
- JournalTOCs
- ResearchBible
- Ulrich's Periodicals Directory
- Access to Global Online Research in Agriculture (AGORA)
- Electronic Journals Library
- RefSeek
- Hamdard University
- EBSCO A-Z
- OCLC- WorldCat
- SWB online catalog
- Virtual Library of Biology (vifabio)
- Publons
- MIAR
- Geneva Foundation for Medical Education and Research
- Euro Pub
- Google Scholar
Useful Links
Share This Page
Journal Flyer
Open Access Journals
- Agri and Aquaculture
- Biochemistry
- Bioinformatics & Systems Biology
- Business & Management
- Chemistry
- Clinical Sciences
- Engineering
- Food & Nutrition
- General Science
- Genetics & Molecular Biology
- Immunology & Microbiology
- Medical Sciences
- Neuroscience & Psychology
- Nursing & Health Care
- Pharmaceutical Sciences
Anand Setty Balakrishnan
Anand Setty Balakrishnan
School of Biotechnology,
India
Publications
-
Research Article
In-vitro Evaluation of Thymol Derived from Trachyspermum ammi against Acetaminophen Induced Hepatotoxicity Towards Lymphatic Filariasis Therapeutics
Author(s): Abel Arul Nathan and Anand Setty Balakrishnan*Abel Arul Nathan and Anand Setty Balakrishnan*
Individuals with lymphatic filariasis (LF) shows elevated levels of pro-inflammatory cytokines, altered expressions of inflammatory genes and are prone to secondary bacterial infection. Also markers of liver dysfunction were reported to be high with increased filarial infection. Acetaminophen (Paracetamol), an anti-pyretic drug was prescribed to LF individuals along with Diethylcarbamazine and Albendazole to alleviate pain and filarial fever within the therapeutic dosage. It is unclear, whether parasite secreted toxins augments the action of acetaminophen and enhances liver dysfunction. Hence, an agent which can attenuate the acetaminophen toxicity during filarial infection is warranted. Trachyspermum ammi (T. ammi) is the richest source of thymol, reported to have anti-filarial lead molecule. In the present study we evaluated the effects of thymol against acetaminophen induced hepato.. View More»
DOI: 10.4172/2155-9597.1000322