Amr Aziz
Egypt
Research Article
Recurrent Hepatitis C Virus (Genotype 4) Infection after Living Donor Liver Transplantation: Risk Factors and Outcome
Author(s): Emad Hamdy Salem, Mohammed Taha, Amr Aziz, Ayman Alsebaey, Khaled Abou El-Ella and Tarek Ibrahim
Emad Hamdy Salem, Mohammed Taha, Amr Aziz, Ayman Alsebaey, Khaled Abou El-Ella and Tarek Ibrahim
Objectives: The recurrence of HCV post liver transplantation endangers patient and graft survival. The aim of this study is to analyze the risk factors for HCV recurrence, the effect of the recurrence and its management on the outcome of liver transplantation.
Materials and methods: After exclusion of the 6 months mortality, dual HCV and HCC patients, about fifty five HCV related LDLT patients were enrolled in the study and were followed up from 6 to 60 months. Demographic, preoperative, intraoperative and postoperative data were studies. HCV recurrence was defined by elevated transaminases, positive serum HCV RNA and liver biopsy findings. Univariate and multivariate analysis were done on all data to detect the favoring factors of HCV recurrence.
Results: HCV recurrence occurred in 21/55 of the patients and one of.. View More»
DOI:
10.4172/2167-0889.1000148