Amit Tiwari
Tanzania
Research Article
In vivo Studies for Drug Development via Oral Delivery: Challenges,
Animal Models and Techniques
Author(s): Katherine Brake, Ashwini Gumireddy, Amit Tiwari, Harsh Chauhan and Dunesh Kumari
Katherine Brake, Ashwini Gumireddy, Amit Tiwari, Harsh Chauhan and Dunesh Kumari
Drug discovery and development involves a complex iterative process of new molecules synthesis, formulations, and in vitro analysis, followed by biochemical and cellular assays, with final validation in animal models, and ultimately in humans. The purpose of this article is to present a concise overview of the rationale and challenges for performing In vivo studies, the types of animal models, and modern In vivo research techniques for oral drug delivery.
.. View More»
DOI:
10.4172/2153-2435.1000560