Alzahrani AM
Saudi Arabia
Research Article
Adherence to Hydroxyurea Therapy in Patients with Sickle Cell Disease at King Khalid University Hospital in Riyadh
Author(s): Alkanhal HN, Bakrman AK, Alzahrani AM, Alotaibi MS, Bin Salamah AA, AlHejjei SA and Al-Anazi KAAlkanhal HN, Bakrman AK, Alzahrani AM, Alotaibi MS, Bin Salamah AA, AlHejjei SA and Al-Anazi KA
Background: Sickle cell disease is associated with several systemic complications and life-threatening crises. The use of drugs that increase hemoglobin F level, such as hydroxyurea, in patients with sickle cell disease is associated with a reduction in the severity of the disease.
Aim: To compare the outcome of patients adherent to hydroxyurea with those who are poorly adherent and to determine which age group is more likely to be poorly adherent and hence suffer more complications.
Subjects and Methods: A cross-sectional study was performed at King Khalid University Hospital in Riyadh between January 01 and March 31, 2014. The study included 140 patients, 60 of them were receiving hydroxyurea therapy.
Results: Patients who were adherent to hydroxyurea treatment suffered less complicatio.. View More»