Journal of Blood Disorders & Transfusion

Alin Horatiu Muresean

Publications

• Case Report
  Hypothyroidism-Associated Autoimmune Thyroiditis and Papillary Thyroid Cancer
  Author(s): Ancuta Augustina Gheorghisan-Galateanu, Mara Carsote, Dana Terzea, Ana Valea, Dan Peretianu, Alin Horatiu Muresean and Adina GhemigianAncuta Augustina Gheorghisan-Galateanu, Mara Carsote, Dana Terzea, Ana Valea, Dan Peretianu, Alin Horatiu Muresean and Adina Ghemigian
  
  Autoimmune thyroiditis (AI) and differentiated thyroid cancer as papillary type (PTC) are sometimes associated and several common pathogenic mechanisms have been described: BRAF mutations, hOGG1 loss of heterozygosity, interleukin-10 activation, selenoproteomas disturbances. Controversies are related to a more aggressive profile of PTC if AI is presented by interferences with oxidative stress and secondary carcinogenesis. This is a case report of a 37-year old female diagnosed a decade ago with multi-nodular goiter and hypothyroidism. She was treated in different endocrine centers. She started to accuse intermittent breathing difficulties which were not related to her previous diagnosis of asthma. On admission, the thyroid function was normal under levothyroxine (LT4) therapy with high anti-thyreoperoxidase antibodies levels of 1000 UI/mL (Normal<35) co.. View More»
  DOI: 10.4172/2155-9864.1000337

  Abstract PDF