Aliaё AR Mohamed-Hussein
Faculty of Medicine,
Egypt
Research Article
Serum Transforming Growth Factor – β1 (TGF- β1) in Asthmatics: Association between Disease Control, Severity and Duration
Author(s): Neveen Abd El-Moneum Hassan, Aliaё AR Mohamed-Hussein, Ebtssam F. Mohammed, Omnia Abd El-Moneum Mohamed, Hanan O. Mohamed and Manal Mohamed Tammam MahmoudNeveen Abd El-Moneum Hassan, Aliaё AR Mohamed-Hussein, Ebtssam F. Mohammed, Omnia Abd El-Moneum Mohamed, Hanan O. Mohamed and Manal Mohamed Tammam Mahmoud
Rationale: Asthma is a chronic inflammatory disorder of the airways in which many cells and cellular elements play
a role. Assessment of airway remodelling by analysis of blood and sputum markers has been developed as non-invasive
procedures to bypass tissue biopsy.
Aim of the work: evaluate the usefulness of estimation of serum TGF-β1, as non- invasive markers of airway
remodelling in patients with bronchial asthma and correlation between its level and degree of asthma control, severity
and duration.
Patients and Methods: the study included 68 asthmatics and 20 controls. They were classified according to level
of control, severity and duration. Blood samples were taken to estimate the serum levels of TGF-β1.
Results: the serum level of TGF-β1 was significantly higher in .. View More»
DOI:
10.4172/2161-1009.1000200