Journal of Liver

Alberto R Osella

Publications

• Research Article
  Increased Serum Levels of Oxidative Stress Markers in Patients with Liver Steatosis
  Author(s): Maria Notarnicola, Valeria Tutino, Alberto R Osella, Caterina Bonfiglio, Vito Guerra and Maria Gabriella Caruso Maria Notarnicola, Valeria Tutino, Alberto R Osella, Caterina Bonfiglio, Vito Guerra and Maria Gabriella Caruso
  
  Background: Several studies have suggested that oxidative stress could play a role in the pathogenesis of nonalcoholic fatty liver disease and more precisely in the transition between simple fatty liver and steatohepatitis. Aim: This study aims to investigate if circulating levels of oxidative stress markers could be clinically associated with liver steatosis. Materials and methods: We present data obtained from a subsample of 70 subjects with liver steatosis enrolled by a nutritional trial, called NUTRIEPA study. Serum levels of oxidative stress markers were evaluated by ELISA assay. The diagnosis and the degree of liver steatosis were based on laboratory and ecographic measurements. Statistical methods included Kruskal-Wallis analysis of variance and, Wilcoxon signed-rank or Mann-Whitney test, where appropriate. .. View More»
  DOI: 10.4172/2167-0889.1000127

  Abstract PDF