Journal of Microbial & Biochemical Technology

Abraham Tesfaye Bika

Publications

• Research Article
  Comparison of GeneXpert against Light-Emitting Diode Fluorescent Microscopy for the Diagnosis of Pulmonary Tuberculosis in Addis Ababa, Ethiopia
  Author(s): Boja Dufera Taddese, Daniel Melese Desalegn, Abay Sisay Misganaw, Kumera Terfa Kitila, Hanna Mekonnen Balcha, Chalachew Sisay Gebeyehu, Tinsae Kidanemariam Hailu and Abraham Tesfaye BikaBoja Dufera Taddese, Daniel Melese Desalegn, Abay Sisay Misganaw, Kumera Terfa Kitila, Hanna Mekonnen Balcha, Chalachew Sisay Gebeyehu, Tinsae Kidanemariam Hailu and Abraham Tesfaye Bika
  
  Background: Tuberculosis remains a global health problem despite availability of effective tools. Globally, there were 40% of the 10+ million patients with TB did not get diagnosed or notified. The study was aimed to compare the diagnostic performances of iLED-FM and GeneXpert test for the diagnosis of PTB in Addis Ababa, Ethiopia. Methods: Facility-based cross-sectional study was conducted on a total of 286 sputum samples collected from health centers and hospitals clients with presumptive TB from December 2016 to March 2017. Kappa value, Sensitivity, Specificity, Positive Predictive Value (PPV) and Negative Predictive Value (NPV) of iLED-FM and GeneXpert were calculated against the gold standard. Results: The sensitivity, specificity, PPV and NPV of iLED-FM was 80.15%, 95.48%, 93.75% and 85.06%, for GeneXpert 88.55%,.. View More»
  DOI: 10.4172/1948-5948.1000388

  Abstract PDF