Journal of Liver

Abeer Sharaf EL-Din Abd El-Rehim

Publications

• Research Article
  The Impact of Serum Interleukin-17 on Chronic Hepatitis C and Its Sequelae
  Author(s): Elham Ahmed Hassan, Abeer Sharaf EL-Din Abd El-Rehim, Asmaa Omar Ahmed, Nahla Mohamed Elsherbiny and Noha Abd El-Rehim Abo Elhagag Elham Ahmed Hassan, Abeer Sharaf EL-Din Abd El-Rehim, Asmaa Omar Ahmed, Nahla Mohamed Elsherbiny and Noha Abd El-Rehim Abo Elhagag
  
  Background: Recently, interleukin-17 (IL-17) cytokine family plays important roles in the host immunity in chronic inflammatory conditions, autoimmune and viral liver diseases. However, studies on the IL-17 role in the immunopathogenesis of hepatitis C virus (HCV) infection are limited. Objectives: to assess serum IL-17 levels in chronically HCV infected patients and their relations to the severity of liver disease. Patients and methods: The study included 200 chronically HCV infected patients; 100 chronic hepatitis C, 100 liver cirrhosis including 35 with hepatocellular carcinoma (HCC) and 30 controls. Serum IL-17 levels were quantified by ELISA. Results: Serum IL-17 levels were significantly higher in chronically HCV infected patients than controls and cirrhotics had the highest levels .. View More»
  DOI: 10.4172/2167-0889.1000163

  Abstract PDF